![]() Information about allele frequencies of blood groups among different populations worldwide will help in framing policy decisions to face future challenges in healthcare services. Conclusions The distribution of the two major blood group systems namely ABO and Rh (D) systems show considerable heterogeneity in different populations of the world. The allele frequencies of ABO and Rh (D) blood groups were 0.1628 for IA, 0.2177 for IB, 0.6259 for IO, 0.7991 for ID, and 0.2009 for Id. A majority (95.96%) of the blood donors were Rh (D) positive. The phenotypic frequency of blood group O (39.17%) was the highest and that of blood group AB (7.88%) was the least. The most common blood group was O positive (37.67%) while AB negative (0.18%) was the least common blood group. Results Out of total a of 7598 blood donors, 7576 (99.71%) were males and 22 (0.29%) were females. Allele frequency of the blood group genes was calculated based on Hardy-Weinberg equilibrium. ABO and Rh (D) blood grouping of all the blood donors were carried out by tube agglutination method. Methods This was a retrospective observational study carried out in the blood bank of Karpaga Vinayaga Institute of Medical Sciences and Research Centre from January 2015 to December 2021. The objective of the study is to estimate the distribution of ABO & Rh (D) blood groups among all the blood donors in a tertiary care hospital in Chengalpattu district of Tamilnadu in South India and to determine their allele frequencies. Introduction The distribution of ABO and Rh (D) blood groups and their allele frequencies vary from one population to another worldwide. O+ > A+ > B+ > O-> AB+> A-> B- > AB- was found to be the order of blood group frequency in the current study. The frequency of the blood type A was the second highest, followed by the blood group B, whereas Rh positivity was more common than Rh negativity. The findings in this study showed that O was the most prominent ABO blood group, whereas AB was the least so. Commercially provided anti-A, anti-B and anti-D antibodies were used for the standard blood grouping procedure. This study was performed during the period of January 1, 2020, to December 31, 2020, using samples from 4167 voluntary subjects obtained from the blood bank of the King Abdullah Hospital, Bisha. Understanding the frequency of different blood types in different populations is imperative. The impetus of this study was to develop an understanding of the distribution of the ABO and Rh types of healthy volunteer blood donors in the northern Asir region of Saudi Arabia, comparing the findings to similar studies. Distribution of ABO and Rh among the Saudi population could affect many factors such as blood transfusion, prognosis, resistance and susceptibility to diseases. In humans, this is the most important of the 43 different blood type (or group) classification systems currently recognized. ![]() ![]() The ABO blood group system is used to denote the presence of one, both, or neither of the A and B antigens on erythrocytes. The findings of the ABO blood group in this study were comparable to other studies conducted in Ethiopia. The knowledge of the distribution of blood groups is very important for blood banks and transfusion services which play an important role in the patient's health care. The Rh-positive donors were more prevalent (94.82%) as oppose to the Rh-negative (5.18%). The antigen frequencies of ABO and Rh(D) blood group system showed that O was the most prevalent blood group 44.65% followed by A (28.41%), B (21.24%), and AB (5.71%). The majority of the donors belonged to the age group between 18 and 25 years old (53%). An ethical clearance letter was obtained from Addis Ababa University and informed consent was also obtained from the participants of the study.Ī total of 1700 donors were included, of which 57% of donors were males. Data processing and analysis were undertaken by using Statistical Package for the Social Sciences (SPSS) version 26. All tests were performed using fully automated immunohematology analyzer (Galileo Neo Immucor). To determine the prevalence ABO and Rh blood groups Among Volunteer Blood Donors at Ethiopian blood and tissue bank service (EBTBS), Addis Ababa.Ī cross-sectional study was carried out from January 2022 to May 2022, on 1700 volunteer blood donors to assess prevalence of ABO and Rh blood groups among volunteer blood donors at the Ethiopian blood and tissue bank service. Blood group antigens are found on the surface of red blood cells that are inherited biological characteristics that do not change throughout life in healthy individuals. The discovery of the ABO blood group system and testing of blood donors highly reduced the fatalities associated with blood transfusion reactions and improved the safety of blood transfusion.
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